Application of a 0. You rub a pea-sized dot of cream on the fissure twice a day. It is a good idea to either wear gloves when applying the nitroglycerin cream or wash your hands right after. The skin on your fingers can absorb the medicine and increase your chance of side effects.
Nitroglycerin (Rectal Route) Description and Brand Names - Mayo Clinic
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0.4% nitroglycerin ointment : in the treatment of chronic anal fissure pain.
Anal Fissures: A Real Pain. Patients with anal fissures frequently seek care for pain. Anal fissures also called fissure in ano are a common affliction— second only to hemorrhoids in terms of patient complaints about the anus. However, researchers have been unable to estimate the true incidence of anal fissures. Anal fissures occur only rarely in patients older than 65 years.
Nitroglycerin rectal ointment is used to relieve moderate to severe pain caused by chronic anal fissures. An anal fissure is a tear in the skin around the opening for bowel movements, also known as the anus or rectal area. Nitroglycerin belongs to the group of medicines called nitrates. It works to relax the muscles around the anus so there is less pressure in the area.